Mercury-induced Autoimmunity: Genetics and Immunoregulation
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Allergy and Autoimmunity Caused by Metals: A Unifying Concept
Allergy and autoimmunity are caused by an abnormal immune response and have the same clinical outcomes, including local and systemic inflammation resembling autoimmune/inflammatory syndrome induced by adjuvants (ASIA) (Shoenfeld and Agmon-Levin, 2011; Perricone et al., 2013). This chapter will give an overview of the literature on metal-induced pathologies, such as delayed-type hypersensitivity...
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The diverse genetic backgrounds of lupus-prone murine models, which produce both quantitative and qualitative differences in disease expression, may be a valuable resource for studying the influence of environmental exposure on autoimmune disease in sensitive populations. We tested this premise by exposing autoimmune-prone BXSB and the nonautoimmune C57BL/6 mice to the heavy metal mercury. Alth...
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تاریخ انتشار 2004